The most common daily dose of Anapolon is 100mg, but even at that dosage side-effects like water-retention, elevated blood pressure, acne, hair loss, blood clotting changes, gynocomastia, liver toxicity and mood swings are very often reported. Using aromatase inhibitors to control estrogen aromatization will be ineffective as this drug does not directly convert into estrogen. It was suggested that oxymetholone can activate the estrogen receptor, similar to, but more profoundly than the estrogenic androgen methandriol. Supplements like Milk Thistle can be taken to help keep liver enzyme levels between safe ranges.
As previously noted, cholesterol levels can change when oral steroids are used, even for short periods. Recent research has pointed the finger at cholesterol as being one of the most important steroid related side effects bodybuilders want to avoid. The thickening of the blood (red blood count RBC), artery plaque, high blood pressure, high LDL and low HDL can and will lead to coronary heart disease (CHD) if adequate precautions aren’t taken. It is thus advised; all oral steroids are taken for cycles of 6-8 weeks and no longer. Support supplements are also advised, these include: Curcumin, Citrus Bergamot, Vitamin K2, Omega-3.