Trenbolone acetate (short half-life)
Trenbolone has been used by veterinarians for animals to increase muscle growth and appetite.
It exhibits strong anabolic and androgenic effect which is accompanied by significant lipotropic effects flavored. Causes an increase in strength without excessive weight gain, it follows that almost no water retention in the body, its great peculiarity is that it burns fat while at the same time in parallel with this action builds big, strong and hard muscles. It supports protein synthesis.
Regarding side effects, of course there are also androgenic contingent problems - acne, headaches, enormous aggression and mood swings, testicular atrophy, hair loss, prostate enlargement. Quite strongly influences the formation of testosterone, which can lead to sexual dysfunction. Other side effects include insomnia and night sweats. To be included among the highly toxic agents. When trenbolone indicated high harmful to the kidneys (beware of strong dark urine, blood in urine or tingling in the kidney). It is therefore necessary to take enough fluids (3-5 liters per day). It is worth mentioning also that the enormous harmful to the kidneys was nothing demonstrated, that there may also be a myth. Trenbolone acetate solubility in vegetable oil is 50 mg / ml. If benzyl alcohol as used to increase the solubility, the concentration can be increased to 75-100 mg / ml. The disadvantage of concentrations above 50 mg / 1 mL, frequent short cough that lasts for about one minute after injection.
Since Trenbolone Acetate has a short half-life (1 to day), administered every or every other day in approximate doses of 50-150 mg. The most commonly used at the time of 4-6 weeks, maximum for the acetate form, however, is 8 weeks. Detection time is 9 months.
Exogenous growth promoters have been used in US beef cattle production for over 50 yr. The environmental fate and transport of steroid growth promoters suggest potential for endocrine-disrupting effects among ecological receptors; however, the initial excretion of steroid metabolites from cattle administered growth promoters has not been well characterized. To better characterize excretion of trenbolone acetate and estrogen metabolites, steers were assigned to 1 of the following treatment groups: control, given no implant, or treatment, administered a combination implant (200 mg trenbolone acetate, 40 mg estradiol). Blood, urine, and fecal samples were collected over the course of 112 d following implantation. Samples were extracted and analyzed by liquid chromatography tandem mass spectrometry for trenbolone acetate and estrogen metabolites. In both urine and feces, 17α-trenbolone and 17α-estradiol were the predominant metabolites following implantation. Mean concentrations of 17α-trenbolone and 17α-estradiol in feces of implanted steers were ± ng/g and ± ng/g, respectively. A best-fit model is presented to predict 17α-trenbolone and 17α-estradiol excretion from steers receiving implants. The present study provides the first characterization of both trenbolone and estrogen metabolites in excreta from implanted cattle and will help provide estimates of steroid production from feedyards in the United States. Environ Toxicol Chem 2014;33:2850–2858 . © 2014 SETAC
Some bodybuilders and athletes use trenbolone esters for their muscle-building and otherwise performance-enhancing effects.  Such use is illegal in the United States and many other countries. The DEA classifies trenbolone and its esters as Schedule III controlled substances under the Controlled Substances Act .  Trenbolone is classified as a Schedule 4 drug in Canada  and a class C drug with no penalty for personal use or possession in the United Kingdom .  Use or possession of steroids without a prescription is a crime in Australia .  The infamous "duchess" cocktail administered to Russian athletes at the Sochi Winter Olympics consisted of oxandrolone , a metenolone ester, and a trenbolone ester.