Injectable steroids are injected into muscle tissue, not into the veins. They are slowly released from the muscles into the rest of the body, and may be detectable for months after last use. Injectable steroids can be oil-based or water-based. Injectable anabolic steroids which are oil-based have longer half-life than water-based steroids. Both steroid types have much longer half-lives than oral anabolic steroids. And this is proving to be a drawback for injectables as they have high probability of being detected in drug screening since their clearance times tend to be longer than orals. Athletes resolve this problem by using injectable testosterone early in the cycle then switch to orals when approaching the end of the cycle and drug testing is imminent.
Like other AAS, boldenone is an agonist of the androgen receptor (AR).  The activity of boldenone is mainly anabolic , with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.  Boldenone was synthesized in an attempt to create a long-acting injectable metandienone , for androgen deficiency disorders. Boldenone acts similar to metandienone with fewer adverse androgenic effects. [ medical citation needed ] Although commonly compared to nandrolone , boldenone lacks progesterone receptor interaction and associated progestogenic side effects.
Excessive decrease in blood pressure; patients with hypovolemia and hyponatremia
Irbesartan rarely cause an excessive fall in blood pressure in hypertensive patients without other comorbidities. As well as taking ACE inhibitors, may be expected to excessive reduction of blood pressure with the corresponding symptoms in patients with hypovolemia and hyponatremia, which include patients undergoing intensive diuretic therapy, and / or patients with limited consumption of salt or patients undergoing hemodialysis. Hyponatremia and hypovolemia should be corrected before treatment with Aprovask ® or should consider the use of lower initial doses.