Steroid dependent colitis

I just lost my 8 year old chihuahua mix. He had no symptoms until a few weeks ago. We were still running tests. Blood work ok, fungal test negative, but very cloudy X-ray. Tracheal wash was inconclusive but mast cells and blood present. Ultrasound showed mass near kidney. His breathing had become a little heavier after exertion. We were scheduling for a ct and had given him a few small dose steroid shots over the past week, one every 3 days to help with appetite because he had quit eating. Two days before he died, his breathing had become a little heavier (never open mouthed though). The Dr had said even if ct confirmed cancer, he probably wouldnt be a candidate for chemo since it had probably spread to the lungs. I decided to go ahead and begin high dose steroids for cancer treatment in the hope of having some quality time with him. After 24 hrs on them, his breathing was more labored and I don’t know if it was from the illness or if the steroids could have caused it. Dr wanted to wait 24 more hrs to see if improvement so I had appt scheduled 48 hrs after starting the high dose steroids. That morning, he barked a few seconds at the door, then coughed a small drop of blood. I grabbed him to head toward the vet and within minutes he began to bleed from his nose and mouth. He died in my arms on the way. He seemed fine and 30 minutes later he was gone. I don’t know if it was his illness (cancer?) that caused this or if the steroids could have done something. I’ve heard of stomach ulcers and blood clots being side effects. Is there any way within 48 hrs of being on them, he could have that type of complication from the drugs? I am heartbroken and in shock. I had little time to process he was sick before he was gone. I am so worried my choosing to go the high steroid route may have caused his death and it was not a peaceful one so I am haunted by it.

The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by Arthur Nobile . [23] [24] [25] The first commercially feasible synthesis of prednisone was carried out in 1955 in the laboratories of Schering Corporation, which later became Schering-Plough Corporation , by Arthur Nobile and coworkers. [26] They discovered that cortisone could be microbiologically oxidized to prednisone by the bacterium Corynebacterium simplex. The same process was used to prepare prednisolone from hydrocortisone . [27]

Treatment: If a pancreatic or liver tumor is identified and able to be surgically excised, the skin lesions may normalize for an extended period of time, but because these tumors metastasize (spread to other areas of the body) quickly, surgery is not curative. In cases of end stage liver disease, surgery is not possible, and the goal of therapy is to increase quality of life and decrease uncomfortable skin lesions with supportive care and addressing the nutritional abnormalities. Supportive care includes supplementing protein and necessary minerals and enzymes through the diet and oral supplements or by weekly intravenous amino acid infusions that are performed in the hospital on an outpatient basis until improvement in the skin is noted. Unfortunately, despite the supportive care, the disease will progress.

1-Vaginal Discharge: yellow, white, pasty and sticky. This changes consistency discharge current during ovulation is different.
Bleeding or spotting after 2-Relationship
3-intermediate pieces no bleeding: excessive swelling and edema of the cervical epithelium, depending on the internal channel would be increased fragility and easily traumatized. This leads vaginal bleeding spots on the end of the shower, or sex.
4-shot lower back pain coccyx
5 burning urination, frequent urination and urinary retention is difficult. This is due to infection of the cervix, lymph yayilmasindandir (by neighborhood) of the urinary bladder. Honeymoon appear Honeymoon cystitis is for these reasons. Frequent intercourse and extremely alert and trauma to the mouth of the uterus, resulting in the formation of urinary problems.
6 Infertility Infertility causes by 10%, primarily due to the factors listed in the mouth of the uterus, cervix and wounds. The infection and changes in the structure of the sperm (male seed) prevents passage of the uterus.
What is the diagnosis of cervical lesions?

Steroid dependent colitis

steroid dependent colitis

1-Vaginal Discharge: yellow, white, pasty and sticky. This changes consistency discharge current during ovulation is different.
Bleeding or spotting after 2-Relationship
3-intermediate pieces no bleeding: excessive swelling and edema of the cervical epithelium, depending on the internal channel would be increased fragility and easily traumatized. This leads vaginal bleeding spots on the end of the shower, or sex.
4-shot lower back pain coccyx
5 burning urination, frequent urination and urinary retention is difficult. This is due to infection of the cervix, lymph yayilmasindandir (by neighborhood) of the urinary bladder. Honeymoon appear Honeymoon cystitis is for these reasons. Frequent intercourse and extremely alert and trauma to the mouth of the uterus, resulting in the formation of urinary problems.
6 Infertility Infertility causes by 10%, primarily due to the factors listed in the mouth of the uterus, cervix and wounds. The infection and changes in the structure of the sperm (male seed) prevents passage of the uterus.
What is the diagnosis of cervical lesions?

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