Osteoporosis is particularly common in smokers, postmenopausal women, the elderly, underweight or immobile, and patients with diabetes or lung problems. Osteoporosis may result in fractures of the spine, ribs or hip joint with minimal trauma. These occur after the first year in 10–20% of patients treated with more than mg prednisone daily. It is estimated that up to 50% of patients on long-term prednisone will develop bone fractures. Vertebral fractures are more common in patients on steroids, even in those with normal bone density.
John Smith, 33 male had sinus surgery four month ago by a top surgeon. He had expected to be free of sinus disease after his surgery, yet he had been sick with sinusitis since his sinus surgery, despite antibiotics. Pulsed irrigation in the office removed thick mucus and colored exudate. He was continued on pulsed irrigation twice a day in order to thin his mucus and restore his cilia He was free of sinus symptoms in three weeks. His post-surgery sinus infection was due to reduced MCC. Slowed MCC is seen frequently after sinus surgery .