Aldolase has also been implicated in many "moonlighting" or non-catalytic functions, based upon its binding affinity for multiple other proteins including F-actin , α-tubulin , light chain dynein , WASP , Band 3 anion exchanger, phospholipase D ( PLD2 ), glucose transporter GLUT4 , inositol trisphosphate , V-ATPase and ARNO (a guanine nucleotide exchange factor of ARF6 ). These associations are thought to be predominantly involved in cellular structure, however, involvement in endocytosis, parasite invasion, cytoskeleton rearrangement, cell motility, membrane protein trafficking and recycling, signal transduction and tissue compartmentalization have been explored.   
WOW, if you going to waste so much time cutting and pasting please do some research first, not this crap. Do you actually understand anything you posted above?
Google Ketosis and then Google Ketoacidosis, and then understand the huge difference. Along the way you should discover that ketosis ISN’T harmful to the kidneys and is actually protective.
In fact, ketone bodies are the bodies prefered fuel mechanism and is the means whereby we evolved to survive. The heart operates much more efficiently on ketones as does much of the brain. We actually all enter ketosis to some degree after a nightly fast or after we haven’t eaten for several hours, and it is perfectly normal.
I have been ketogenic for over 6 years and some of my best workouts have been while fasting, sometimes several days.